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    Androgen signaling in the placenta

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    http://hdl.handle.net/10217/83721
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    Cleys_colostate_0053A_12510.pdf (1.698Mb)
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    Abstract
    Placental estrogen signaling is known to regulate placental trophoblast function and differentiation. However, the role of placental androgen signaling has never been investigated, despite the rise of maternal serum androgens throughout gestation. Recent findings have shown increased maternal serum androgen in patients with the placental induced disorder preeclampsia. Preeclampsia, a maternal hypertension and proteinuria condition instigated by insufficient trophoblast differentiation and invasion into maternal spiral arteries, is also associated with increased placental expression of androgen ...
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    Author(s)
    Cleys, Ellane Rachael

    Advisor(s)
    Bouma, Gerrit; Clay, Colin

    Date Issued
    2014
    Format
    born digital; doctoral dissertations
    Collections
    • 2000-2019 - CSU Theses and Dissertations
    • Theses and Dissertations - Department of Biomedical Sciences

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