Significance of ERα, HER2, and CAV1 expression and molecular subtype classification to canine mammary gland tumor
Canine mammary gland tumor and human breast cancer share many similar features regarding their risk factors, histopathological features, and behavior. Despite the increasing evidence of molecular marker expression as a prognostic factor for human breast cancer, there are only little studies using this approach on canine mammary gland tumor. Our aim was to evaluate the significance of the expression of Estrogen Receptor-alpha, Human Epidermal Growth Factor-2, and Caveolin-1 to the behavior and the clinical outcome of canine mammary gland tumor by Immunohistochemistry. We also assessed the correlation ...
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