Hemocompatibility of hyaluronan enhanced linear low-density polyethylene for heart valve leaflet applications
Heart valve disease is a major concern in both developed countries with advanced ageing populations and undeveloped countries which experience a high incidence of rheumatism leading to valvular disease. To reduce mortality and improve quality of life, heart valve implantations have been widely used to assist in improving function of the native cardiovascular system. While mechanical heart valves and tissue-based heart valves have been successfully used to improve quality of life compared to untreated valvular disease, draw-backs are inherent. Mechanical heart valves are prone to thrombosis and ...
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