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    Coagulation abnormalities in Ehrlichia canis-infected dogs and detection and dynamics of anti-platelet antibodies in thrombocytopenic dogs

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    https://hdl.handle.net/10217/191460
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    Abstract
    Vector-borne diseases affect millions of people and domestic animals worldwide resulting in significant morbidity and mortality rates. In dogs, vector-borne diseases such as Ehrlichia canis can cause a myriad of clinical signs (lethargy, weight loss, and epistaxis) and hematological abnormalities (hyperglobulinemia, thrombocytopenia, and anemia). It has been previously reported that E. canis results in systemic inflammation and vasculitis as well as the formation of immunoglobulin associated platelets or anti-platelet antibodies. It has been theorized that anti-platelet antibodies can deleteriously ...
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    Author(s)
    Shropshire, Sarah

    Advisor(s)
    Lappin, Michael

    Date Issued
    2018
    Format
    born digital; doctoral dissertations
    Collections
    • 2000-2019 - CSU Theses and Dissertations
    • Theses and Dissertations - Department of Clinical Sciences

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