Data analysis and predictive modeling for synthetic and naturally occurring biological switches
Biological switches are biochemical network motifs responsible for determining the chemical state of cells, and are a key part of every biological system. The impact of these biological switches on cell behavior is broad. For example, many diseases such as cancer are thought to be caused by a misregulation of the bio-chemical state in a cell or group of cells. Also cell fates in differentiating stem cells are controlled by biological switches. Because of their general importance the synthetic biology community has also constructed synthetic biological switches in living organisms. While there ...
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Schaumberg, Katherine A.
Prasad, Ashok; Medford, June