Mathematical Models for HIV-1 Viral Capsid Structure and Assembly
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HIV-1 (human immunodeﬁciency virus type 1) is a retrovirus that causes the acquired immunodeﬁciency syndrome (AIDS). This infectious disease has high mortality rates, encouraging HIV-1 to receive extensive research interest from scientists of multiple disciplines. Group-specific antigen (Gag) polyprotein precursor is the major structural component of HIV. This protein has 4 major domains, one of which is called the capsid (CA). These proteins join together to create the peculiar structure of HIV-1 virions. It is known that retrovirus capsid arrangements represent a fullerene-like structure. These ...