- ItemOpen AccessDatabase used for creation of antimicrobial resistance and virulence bait-capture panel(Colorado State University. Libraries, 2017) Morley, Paul; Belk, Keith; Noyes, NoelleThese 2 databases were used for design and validation of a bait-capture system for enrichment of antimicrobial resistance and virulence genes within metagenomic samples.
- ItemOpen AccessCanine lymphoma case control database(Colorado State University. Libraries, 1989-2011) Ruple, Audrey A.; Morley, Paul, S.These data were collected by the Veterinary Medical Database and include demographic information about 67,712 dogs seen at veterinary teaching hospitals in North America between 1989 and 2011. 18,826 of these dogs were diagnosed with lymphoma (cases) and the control series were matched to case dogs by institution of admission, age, and year of admission in up to a 3:1 ratio.
- ItemOpen AccessAssociations between Escherichia coli isolate antimicrobial resistance and antimicrobial usage(Colorado State University. Libraries, 2007-09-2010-01) Benedict, Katharine M.; Gow, Sheryl P.; McAllister, Tim A.; Booker, Calvin W.; Hannon, Sherry J.; Checkley, Sylvia L.; Noyes, Noelle R.; Morley, Paul S.Escherichia coli was isolated from the feces of beef cattle from four commercial feedlots in Alberta, Canada. A total of 2,725 isolates were collected from 923 individuals. Antibiotic susceptibility of these isolates to 19 different antimicrobial drugs was determined by broth microdilution and/or disk diffusion assay. Antimicrobial use data was recorded for each feedlot, and associations between antimicrobial resistance and antimicrobial use were determined (see Table 5 in associated publication). Antimicrobial resistance and usage data used to determine associations are reported in this database.
- ItemOpen AccessEscherichia coli individual antimicrobial resistance prevalences(Colorado State University. Libraries, 2007-09-2010-01) Benedict, Katharine M.; Gow, Sheryl P.; McAllister, Tim A.; Booker, Calvin W.; Hannon, Sherry J.; Checkley, Sylvia L.; Noyes, Noelle R.; Morley, Paul S.Escherichia coli was isolated from the feces of beef cattle from four commercial feedlots in Alberta, Canada. Each individual was sampled twice, once upon arrival to the feedlot, and again at ≥33 days on feed (DOF). A total of 2,725 isolates were collected from 923 individuals. Antibiotic susceptibility of these isolates to 19 different antimicrobial drugs was determined by broth microdilution and/or disk diffusion assay. Prevalence of resistance to each drug, by sampling time, was calculated (see Figure 2 in associated publication). Data used for determination of prevalences are reported in this database.
- ItemOpen AccessComparison of NK-1 receptor antagonist (Maropitant) to morphine as a preanaesthetic agent for canine ovariohysterectomy(Colorado State University. Libraries, 2015) Marquez, Megan; Boscan, Pedro; Weir, Heather; Vogel, Pamela; Twedt, David C.Objective: To compare the NK-1 receptor antagonist maropitant to morphine during and after surgery in dogs undergoing ovariohysterectomy (OHE). Methods: 30 healthy female dogs were randomly divided to receive either a pre-anaesthetic dose of morphine (0.5 mg/kg SQ) or maropitant (1 mg/kg, SQ) prior to OHE. Anaesthesia was induced with propofol and maintained with isoflurane. Expired isoflurane concentration, heart rate (HR), systolic arterial pressure (SAP) and respiratory rate were measured. Post-operative pain scores and appetite were evaluated during the recovery period. Rescue analgesia (morphine 0.1 mg/kg IV) was administered as needed post-operatively based on blinded pain score assessments. Results: Although clinically comparable; during surgical stimulation, the maropitant group had lower HR (108±18 vs 115±24 bpm; p=0.04), lower SAP (114±23 vs 125±23 mmHg; p=0.003) and required slightly lower percent of isoflurane anaesthetic (1.35±0.2 vs 1.51±0.4 %; p=0.005), when compared to the morphine group. In the recovery period, the maropitant group had lower pain scores at extubation (1.7±0.7 vs 3.4±2.3; p=0.0001) and were more likely to eat within 3 hours after extubation (64.7 vs 15.3%). However, post-operative rescue analgesia requirements were similar between groups. All other measured parameters were similar between groups. The overall difference observed between groups was small and all monitored and measured parameters were within the expected range for anesthetized dogs. Clinical Significance: No major differences in cardiorespiratory parameters or anaesthetic requirements were observed between maropitant and morphine when used as a pre-anesthetic agent for OHE. Further studies are necessary to fully elucidate the benefits of maropitant as a pre-anaesthetic agent for canine OHE.