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Role of stress-responsive genes in the molt cycle of decapod crustaceans

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dc.contributor.authorLópez-Cerón, Diego Alejandro, author
dc.contributor.authorMykles, Donald, advisor
dc.contributor.authorGarrity, Deborah, committee member
dc.contributor.authorKanatous, Shane, committee member
dc.contributor.authorDi Pietro, Santiago, committee member
dc.date.accessioned2020-01-13T16:42:14Z
dc.date.available2021-01-07T16:41:53Z
dc.date.issued2019
dc.description.abstractThe main objective of this study was to understand the molecular mechanisms underlying the inhibition of molting by environmental stress in decapods. The general hypothesis describes that environmental stressors inhibit synthesis and secretion of molting hormones (ecdysteroids) by the molting gland, or Y-organ (YO), through stress response signaling genes in the mTOR signaling pathway. It is predicted that premolt animals of Gecarcinus lateralis will be more sensitive to thermal stress compared to those in intermolt stages, and that G. lateralis will be more sensitive to environmental stresses such as temperature or desiccation than Carcinus maenas. The aims of this study were to review of state of the art on molting in decapods, regulation of molt cycle by environmental stress, design of model of stress response in decapods (Chapter 1), Isolate, identify and characterize cDNAs encoding stress response genes in G. lateralis and C. maenas (Chapter 2), Quantify the effects of acute thermal stress on the Y-organ of Multiple Leg Autotomy (MLA) and Eyestalk Ablated (ESA) intermolt, premolt, and postmolt G. lateralis (Chapter 3), and Quantify the effects of desiccation on gene expression and mTOR activity in intermolt animals of C. maenas (Chapter 4).
dc.format.mediumborn digital
dc.format.mediumdoctoral dissertations
dc.identifierLxF3pezCerxF3n_colostate_0053A_15838.pdf
dc.identifier.urihttps://hdl.handle.net/10217/199858
dc.languageEnglish
dc.language.isoeng
dc.publisherColorado State University. Libraries
dc.relation.ispartof2000-2019
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.subjectresponse
dc.subjectY-organ
dc.subjectmolt cycle
dc.subjectecdysteroid
dc.subjectstress
dc.subject.lcshGecarcinus
dc.titleRole of stress-responsive genes in the molt cycle of decapod crustaceans
dc.typeText
dcterms.embargo.expires2021-01-07
dcterms.embargo.terms2021-01-07
dcterms.rights.dplaThis Item is protected by copyright and/or related rights (https://rightsstatements.org/vocab/InC/1.0/). You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
thesis.degree.disciplineBiology
thesis.degree.grantorColorado State University
thesis.degree.levelDoctoral
thesis.degree.nameDoctor of Philosophy (Ph.D.)

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