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Dose reconstruction in the large Japanese field mouse using electron paramagnetic resonance spectroscopy of tooth enamel

dc.contributor.authorDavis, Mariah, author
dc.contributor.authorJohnson, Thomas, advisor
dc.contributor.authorBrandl, Alexander, committee member
dc.contributor.authorGelfand, Martin, committee member
dc.date.accessioned2020-09-07T10:08:54Z
dc.date.available2020-09-07T10:08:54Z
dc.date.issued2020
dc.description.abstractElectron spin resonance (ESR) analysis of tooth enamel is recognized as a reliable method for lifetime dose reconstruction, particularly in human tooth enamel. While the use of ESR to reconstruct dose is well understood for human tooth enamel, the reliability and usefulness of dose reconstruction using ESR in mouse tooth enamel has not been as thoroughly studied. This paper aims to resolve this gap in knowledge concerning the use of the tooth enamel from the Large Japanese Field Mouse as acting dosimeter using EPR spectroscopy. Methods of tooth preparation were analyzed to find a preparation method that resolved a baseline shift or slope in output signals of preliminary samples. Use of purity EDTA (ethylenedinitrilotetraacetic acid, disodium salt dihydrate) was initially found to reduce an observed baseline shift and slope in the output spectrum. Subsequent samples treated with EDTA, however, again saw baseline shifts. More needs to be done to analyze appropriate methodology to reduce the baseline shift, and to further determine the suitability of mouse teeth for ESR spectroscopy for reconstruction of lifetime dose.
dc.format.mediumborn digital
dc.format.mediummasters theses
dc.identifierDavis_colostate_0053N_16248.pdf
dc.identifier.urihttps://hdl.handle.net/10217/212073
dc.languageEnglish
dc.language.isoeng
dc.publisherColorado State University. Libraries
dc.relation.ispartof2020-
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.subjectelectron spin resonance
dc.subjectelectron paramagnetic resonance
dc.subjectlarge Japanese field mouse
dc.titleDose reconstruction in the large Japanese field mouse using electron paramagnetic resonance spectroscopy of tooth enamel
dc.typeText
dcterms.rights.dplaThis Item is protected by copyright and/or related rights (https://rightsstatements.org/vocab/InC/1.0/). You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
thesis.degree.disciplineEnvironmental and Radiological Health Sciences
thesis.degree.grantorColorado State University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (M.S.)

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