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Spatial, demographic, and phylogenetic patterns of Bartonella diversity in bats

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dc.contributor.authorMcKee, Clifton Dyer, author
dc.contributor.authorWebb, Colleen T., advisor
dc.contributor.authorKosoy, Michael Y., committee member
dc.contributor.authorFunk, W. Chris, committee member
dc.contributor.authorSchountz, Tony, committee member
dc.contributor.authorHayman, David T. S., committee member
dc.date.accessioned2015-08-28T14:35:22Z
dc.date.available2016-08-14T06:30:24Z
dc.date.issued2015
dc.description.abstractMuch recent attention has focused on bats as potentially exceptional reservoirs of pathogens. Bats are known to carry zoonotic viruses deadly to humans with no apparent signs of pathology, however the evolutionary and physiological processes that are behind this ability remain largely unknown. Despite this uncertainty, bats’ long lifespans, deep evolutionary history, sociality, and migratory behavior make them a fascinating system in which to study patterns of diversity in viruses, bacteria, and other infectious organisms. This thesis explores ecological and evolutionary processes that structure the diversity of infectious bacteria in bats. I focus on Bartonella, a genus of vector-borne intracellular bacteria, because of its high prevalence and genetic diversity within bats. I examined the structure of Bartonella species assemblages in Eidolon spp. fruit bats across Africa and Madagascar using newly developed molecular and statistical tools. The results from this examination indicate that fruit bats from distant geographic locations host similar communities of Bartonella; I attribute this to widespread dispersal and communal roosting behavior in Eidolon spp. bats. To understand how Bartonella diversity has evolved and is structured geographically, I assembled a global dataset of Bartonella genotypes from bats and their ectoparasites. Using this dataset, I analyzed the contributions of cospeciation and sympatry among host species to the diversity of Bartonella in bats. Continued development of this research could provide a model system for the study of ecological and evolutionary processes contributing to pathogen diversification and infection dynamics in natural systems.
dc.format.mediumborn digital
dc.format.mediummasters theses
dc.identifier.urihttp://hdl.handle.net/10217/167162
dc.languageEnglish
dc.language.isoeng
dc.publisherColorado State University. Libraries
dc.relation.ispartof2000-2019
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.subjectcophylogeny
dc.subjectmolecular genetics
dc.subjectdisease ecology
dc.subjectbartonella
dc.titleSpatial, demographic, and phylogenetic patterns of Bartonella diversity in bats
dc.typeText
dcterms.embargo.expires2016-08-14
dcterms.embargo.terms2016-08-14
dcterms.rights.dplaThis Item is protected by copyright and/or related rights (https://rightsstatements.org/vocab/InC/1.0/). You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
thesis.degree.disciplineEcology
thesis.degree.grantorColorado State University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (M.S.)

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