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Occupational experiences and brain health outcomes in older age

dc.contributor.authorJiao, Yuqin, author
dc.contributor.authorBurzynska, Aga Z., advisor
dc.contributor.authorFisher, Gwen G., committee member
dc.contributor.authorBielak, Allison A., committee member
dc.date.accessioned2020-01-13T16:42:11Z
dc.date.available2022-01-07T16:41:53Z
dc.date.issued2019
dc.description2019 Fall.
dc.descriptionIncludes bibliographical references.
dc.descriptionZip file contains supplementary tables.
dc.description.abstractMost adults spend half of their awake time at work. Although greater midlife work complexity has been consistently linked to better cognitive outcomes in older age, little is known about how occupational experiences associate with brain aging. Two studies have found an association between midlife managerial experience and slower hippocampal atrophy in older adults with no (Suo et al., 2012) and mild cognitive impairment (Suo et al, 2016). However, no study has considered to include both protective (enriching) and risk (stress-related) occupational factors in relation to neurocognitive health in aging, which we recently conceptualized as the BOSS model (Brain aging: Occupational Stimulation and Stress; Burzynska, Jiao, Ganster, 2018). To empirically test this model, we assessed five stimulating and stress occupational constructs to reflect the characteristics of most recent main occupations in 101 cognitively healthy older adults (mean age=70, a subsample of "Fit & Active Seniors Trial (FAST)" trial, clinical study identifier NCT01472744). To obtain the above constructs, we did a priori grouping then factor analysis on 86 items from three well-established occupational experience questionnaires (Spector & Jex, 1998; Morgeson & Humphrey, 2006). We measured hippocampal volume with Magnetic Resonance Imaging and cognitive tasks with Virginia Cognitive Battery and spatial working memory tasks. Greater physical demands at work were associated with smaller bilateral hippocampi and lower performance on spatial working memory tasks, independent of the effects of age, education, estimated total intracranial volume, sensor-measured lifestyle moderate-to-vigorous physical activity, and current employment status. We found no evidence for greater hippocampal volume or better cognition as a function of more stimulating occupational exposures. These findings have furthered our understanding of the neurocognitive correlates of physical demands in healthy older adults and also have highlighted the importance of using longitudinal measures in future studies to decipher the underlying neural mechanisms of occupational exposures.
dc.format.mediumborn digital
dc.format.mediummasters theses
dc.format.mediumZIP
dc.format.mediumPDF
dc.identifierJIAO_colostate_0053N_15831.pdf
dc.identifier.urihttps://hdl.handle.net/10217/199851
dc.languageEnglish
dc.language.isoeng
dc.publisherColorado State University. Libraries
dc.relation.ispartof2000-2019
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.titleOccupational experiences and brain health outcomes in older age
dc.typeText
dcterms.embargo.expires2022-01-07
dcterms.embargo.terms2022-01-07
dcterms.rights.dplaThis Item is protected by copyright and/or related rights (https://rightsstatements.org/vocab/InC/1.0/). You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
thesis.degree.disciplineHuman Development and Family Studies
thesis.degree.grantorColorado State University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (M.S.)

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