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Protein interaction with glycocalyx-mimetic surfaces: a candidate for blood-compatible materials

dc.contributor.authorHedayati, Mohammadhasan, author
dc.contributor.authorKrapf, Diego, author
dc.contributor.authorKipper, Matt J., author
dc.date.accessioned2017-11-13T15:39:57Z
dc.date.available2017-11-13T15:39:57Z
dc.date.issued2017
dc.description.abstractBiomaterials and medical devices induce tissue responses when they get into contact with human blood and rapidly becomes covered with a layer of nonspecifically adsorbed proteins. For blood contacting devices, protein adsorption is undesirable and is generally the first event in blood coagulation. The polymer coating on solid surfaces is an efficient approach for modification of materials to design protein resistant biomaterials. The aim of this work is to mimic the endothelial glycocalyx layer on the surface of blood vessels, which is responsible for anticoagulant activity by restricting molecules such as proteins from reaching the endothelium.en_US
dc.description.awardGreat Minds in Research - 1st Place.
dc.format.mediumborn digital
dc.format.mediumStudent works
dc.format.mediumposters
dc.identifier.urihttps://hdl.handle.net/10217/184854
dc.languageEnglishen_US
dc.language.isoengen_US
dc.publisherColorado State University. Librariesen_US
dc.relation.ispartof2017 Projects
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.titleProtein interaction with glycocalyx-mimetic surfaces: a candidate for blood-compatible materialsen_US
dc.title.alternative128 - Mohammadhasan Hedayatien_US
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