Synthetic and biosynthetic studies of okaramine and hapalindole natural products
Date
2018
Authors
Bair, Nathan Alexander, author
Williams, Robert M., advisor
McNaughton, Brian, committee member
Thamm, Doug, committee member
Sambur, Justin, committee member
Journal Title
Journal ISSN
Volume Title
Abstract
This dissertation is a report on the first total syntheses of hapalindoles C and D, natural products of a few cyanobacteria. Additionally, we report on our collaborative investigations on the biosynthesis of the hapalindole family of natural products. Lastly our efforts toward the total synthesis of okaramines R and B and attempts to synthesize a novel indoloazetidine ring are enclosed.