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What goes down need not go back up: decreasing the biological drive toward weight regain by increasing energy flux

dc.contributor.authorParis, Hunter Louis Ross, author
dc.contributor.authorBell, Christopher, advisor
dc.contributor.authorMelby, Christopher, committee member
dc.contributor.authorHickey, Matthew, committee member
dc.date.accessioned2007-01-03T06:42:44Z
dc.date.available2007-01-03T06:42:44Z
dc.date.issued2014
dc.description.abstractINTRODUCTION: Weight regain after weight loss is the experience of most obese dieters. Metabolic adjustments characterized by decreased resting metabolic rate (RMR) and increased hunger can prevent long-term success. Possibly this energy gap could be attenuated by a high flux (HF) state (higher expenditure coupled with higher intake). METHODS: 6 obese adults [age (mean±SE) = 42±12 y; body mass index (BMI)=35.7±3.7 kg/m2] underwent 7% diet-induced weight loss and were stabilized at this weight for 3 weeks. RMR via indirect calorimetry, and hunger via visual analog scale were then examined during two 4-day conditions of energy balance in random order--Low Flux (LF): sedentary with energy intake (EI)=RMR x1.35; and HF: daily exercise net energy cost of ~500 kcal/d and EI= RMR x1.7. RESULTS: Average 5-day weight did not differ between HF (103.4±4.7 kg) and LF (103±4.8 kg) (P>0.10). Average daily RMR was higher during HF (1926±138 kcal/day) compared to LF (1847±126 kcal/day; P = 0.05). Resting fat oxidation was also higher during HF (0.073+0.010 g/min) compared to LF (0.059+0.012 g/min; P<0.05). Average daily, perceived end-of-day hunger was lower during HF compared to LF (P<0.05). CONCLUSION: These preliminary data suggest that compared to a sedentary LF state of energy balance, a HF energy balance state is associated with a greater RMR, resting fat oxidation, and less hunger - all of which may attenuate the energy gap and protect against weight regain.
dc.format.mediumborn digital
dc.format.mediummasters theses
dc.identifierParis_colostate_0053N_12412.pdf
dc.identifier.urihttp://hdl.handle.net/10217/84047
dc.languageEnglish
dc.language.isoeng
dc.publisherColorado State University. Libraries
dc.relation.ispartof2000-2019
dc.rightsCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.
dc.subjectenergy balance
dc.subjectweight loss
dc.subjectobesity
dc.subjectmetabolism
dc.titleWhat goes down need not go back up: decreasing the biological drive toward weight regain by increasing energy flux
dc.typeText
dcterms.rights.dplaThis Item is protected by copyright and/or related rights (https://rightsstatements.org/vocab/InC/1.0/). You are free to use this Item in any way that is permitted by the copyright and related rights legislation that applies to your use. For other uses you need to obtain permission from the rights-holder(s).
thesis.degree.disciplineHealth and Exercise Science
thesis.degree.grantorColorado State University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (M.S.)

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