RNA interference as an alternative preventive measure for avian influenza in poultry
Avian influenza virus (AIV) is a viral pathogen that causes a wide range of disease in poultry, from subclinical to severe clinical illness and can often result in death. In 1878, AIV was first described as a disease affecting poultry. Nearly 80 years later this disease-causing agent was identified as influenza A virus and a member of the family Orthomyxoviridae. AIV was not considered a significant human pathogen until 1997, when high pathogenic AIV H5N1 emerged from the wildfowl reservoir and was directly transmitted from domestic poultry to humans. Despite a long history of outbreaks in ...
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