Show simple item record

dc.contributor.advisorJohnson, Thomas
dc.contributor.authorScott, Ernie
dc.contributor.committeememberBrandl, Alex
dc.contributor.committeememberWalrond, John
dc.date.accessioned2007-01-03T05:56:53Z
dc.date.available2007-01-03T05:56:53Z
dc.date.issued2013
dc.description2013 Summer.
dc.descriptionIncludes bibliographical references.
dc.description.abstractCurrent methods for diagnosing and evaluating efficacy for treatment of diabetic neuropathy either give only subjective data or are invasive. However, the use of laser induced sensations to evaluate threshold sensations gives precisely quantifiable and reproducible stimulus and is 100% non-invasive. In this study we evaluated whether or not laser sensation thresholds were stable in 12 human subjects over a four month period of time. Subjects' hands and feet were exposed over eight different exposure sessions to 10 ms pulses of laser light produced by a 50 W Tm: YAG laser system. Sensation threshold values (in mJ/mm2) were determined for each session and compared by regression analysis. The results showed an upward trend in sensation thresholds over time in the majority of the subject's hands and feet, indicating that laser sensation thresholds are not stable over time. Subject desensitization to the sensation over time combined with too short a time between exposures, or variations in baseline skin temperature of the exposure site due to changes in weather are discussed as possible causes of the upward trend. Finally, suggestions are made for future studies to include a study over a longer period of time with more time between exposure sessions and more subjects as well as a study where the exposure sites are heated/cooled to a standardized baseline temperature prior to each exposure session.
dc.format.mediumborn digital
dc.format.mediummasters theses
dc.identifierScott_colostate_0053N_11814.pdf
dc.identifier.urihttp://hdl.handle.net/10217/80309
dc.languageEnglish
dc.publisherColorado State University. Libraries
dc.relation.ispartof2000-2019 - CSU Theses and Dissertations
dc.rightsCopyright of the original work is retained by the author.
dc.subjectlaser
dc.subjectthresholds
dc.subjectsensation
dc.subjectneuropathy
dc.titleLong term stability of sensation thresholds from 10 millisecond pulses of 2.01 micrometer laser light
dc.typeText
dcterms.rights.dplaThe copyright and related rights status of this Item has not been evaluated (https://rightsstatements.org/vocab/CNE/1.0/). Please refer to the organization that has made the Item available for more information.
thesis.degree.disciplineEnvironmental and Radiological Health Sciences
thesis.degree.grantorColorado State University
thesis.degree.levelMasters
thesis.degree.nameMaster of Science (M.S.)


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record