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    Brush-like surface using heparin/chitosan based nanoparticles for blood-contacting applications

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    http://hdl.handle.net/10217/80280
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    Abstract
    With increasing applications of biomedical implants, it is crucial to develop surfaces that are blood compatible, meaning they do not induce platelet or protein adhesion. Many implants that are currently used to treat a wide range of problems have one major drawback, they can induce thrombosis. The endothelial glycocalyx plays a crucial role in preventing thrombosis. Based on this idea, we set out to develop a surface that has a brush-like structure similar to that of the endothelial glycocalyx. We developed the surface by adsorbing negatively charged heparin/chitosan polyelectrolyte complex ...
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    Author(s)
    Nijjar, Rajvir Singh

    Advisor(s)
    Kipper, Matt

    Date Issued
    2013
    Format
    born digital; masters theses
    Collections
    • 2000-2019 - CSU Theses and Dissertations
    • Theses and Dissertations - Department of Chemical and Biological Engineering

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