Tick salivary gland proteins (SALPs) as antigens for vaccine development to decrease spirochete load in a murine model of lyme borreliosis
Lyme disease, caused by Borrelia burgdorferi, is the most common tick-borne illness in the United States and selected regions of Eurasia. Members of the Ixodes ricinus complex of ticks are the vectors for B. burgdorferi, with I. scapularis being the primary vector in North America. Lyme disease occurs along the east coast as well as the upper Midwest, with the majority of cases occurring in the northeastern regions of the United States. The number of cases of Lyme disease in the U.S. has increased over the last 20 years with 28,921 cases reported in 2008. Prevention of Lyme disease for humans ...
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