Regulatory T cells in canine cancer
Numbers of regulatory T cells (Treg) are increased in some human malignancies and are often negatively correlated with patient disease-free interval and survival. Canine Treg have previously been identified in healthy and cancer-bearing dogs and have found to be increased in the blood of dogs with some types of cancer. Moreover, some preliminary research indicates that increased numbers of Treg and decreased numbers of CD8+ T cells in the blood of dogs with osteosarcoma (OSA) are associated with decreased survival. The aim of this project was to examine Treg distributions in dogs with cancer ...
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Burton, Jenna Hart
Biller, Barbara J.