Optimization of overhead enclosure monitoring software in a rodent model of osteoarthritis
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Abstract
Osteoarthritis (OA) is a degenerative joint disease characterized by pain, inflammation, and decreased range of motion, leading to impaired activities of daily living and reduced quality of life. OA affects between 250 and 500 million people worldwide, contributing to a substantial and sustained economic burden. Given the global pervasiveness of this poorly understood disease process, in vivo OA research relies on both naturally occurring and induced animal models for its study. The Dunkin Hartley guinea pig spontaneously develops degenerative joint disease as early as 3 months of age and ...
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