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    Investigation of RelBE1 toxin-antitoxin function in the carbon-dependent metabolic adaptation of Mycobacterium tuberculosis

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    https://hdl.handle.net/10217/235595
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    Abstract
    Tuberculosis (TB) is a devastating disease with suboptimal treatment regimens and a single vaccine with variable efficacy. Reducing the global burden of TB requires a refined arsenal of methods to prevent and treat the disease, which necessitates a better understanding of M. tuberculosis (Mtb) pathogenesis during infection. Mtb undergoes continuous metabolic reprogramming throughout acute and chronic stages of infection in order to survive and persist harsh host conditions, and the regulatory network responsible for mediating metabolic adaptation has not been fully defined. Mtb harbors at least ...
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    Author(s)
    Starkey, Julie M.

    Advisor(s)
    Slayden, Richard

    Date Issued
    2022
    Format
    born digital; masters theses
    Collections
    • 2020- CSU Theses and Dissertations
    • Theses and Dissertations - Department of Microbiology, Immunology, and Pathology

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