Tracking infectious prions in the body fluids of deer infected with chronic wasting disease
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Abstract
Chronic wasting disease (CWD) is a prion disease of cervid (elk, moose and deer) with unusually high transmission efficiency. While the nidus of disease was described in a captive herd of cervid in northern Colorado/southeastern Wyoming in the late 60's, it has now been detected in both captive and free-ranging populations in 17 states and 2 Canadian provinces of North America and one Asian country. CWD is unique in being the only transmissible spongiform encephalopathy (TSE) described in a free-ranging population of animals. The etiology of CWD, like all prion diseases, is the conversion of the ...
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