Evaluation of the pharmacodynamics and analgesic efficacy of two buprenorphine formulations in dogs
Pain is an unpleasant and distressing experience. While it serves a protective function for a short period, untreated, ongoing pain has significant detrimental effects. Opioids are one of the most important analgesic agents used for pain management in human and veterinary medicine, with the µ opioid agonists being the most effective for moderate to severe pain. Traditional presentations of µ opioid agonists or partial agonists usually require frequent dosing, which can lead to significant stress due to frequent animal restraint, variability in the level of analgesia and can be labor intensive ...
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