Inactivation of Mycobacterium tuberculosis for safe use outside of the BSL-3 laboratory
Techniques for pathogen inactivation have been long employed by research laboratories to help ease the financial, physical, and health strains associated with (A)BSL-3 work. While robust protocols exist for many of these techniques, there are many holes in research associated with characterization of damage to treated organisms, and standardized methods for comparative analysis of successful sterilization. The work in this thesis aimed to develop methods to better understand current techniques of inactivation. At the same time, it also aimed to characterize the limitations of both a novel approach ...
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