Temporal examination of myoglobin and myosin heavy chain expression patterns in vitro
Myoglobin is a hemoprotein expressed in vertebrate muscle that is typically known to follow an established oxidative muscle fiber type, found in aerobic muscles. However, more recent evidence has demonstrated changes in myoglobin expression without a change in fiber type, indicating myoglobin expression could be regulated by different pathways and may not always be dependent on a prior expressed fiber type. Myoglobin structure is characterized by a globin backbone that supports a nonprotein heme prosthetic group containing iron, which is responsible for the reversible binding of several ligands ...
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