Strategies for targeting cancer: small molecules, epigenetics and drug design
Cancer has plagued our human population since its early characterizations as abnormal cells and tissues in the mid-1900s. Initial treatment models included surgical removal of cancerous tissues. In the late 1960s, surgical removal and localized radiation were the only available options for treatment until the development of chemotherapeutics. These chemical cocktail treatments, designed to kill cancer cells, started in the late-1900s and even today remain a major line of defense in fighting this disease. The goal of the research described in this dissertation was to investigate current methodologies ...
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