Role of α/β hydroxylase domain containing protein 2 in stallion sperm activation
Cell signaling pathways involved in stallion sperm activation are not completely understood. Furthermore, failure of equine in vitro fertilization is commonly attributed to an inability to successfully capacitate sperm. Sperm activation describes the process by which sperm undergo capacitation, hyperactivation, and acrosome reaction in preparation for interaction with an oocyte. 2-arachidonoylglycerol (2AG) is found in the human sperm membrane and prevents calcium influx through the CatSper channel. The α/β hydroxylase domain containing protein 2 (ABHD2) is also found in the human sperm membrane ...
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