Investigating the regulators of cytoplasmic dynein
Organization of the cell is a dynamic and complex process that is often underappreciated. To accomplish this, cells use motor proteins to move different cargo to their destination. Cytoplasmic dynein is one such motor protein that uses filaments called microtubules as tracks. However, there is only one cytoplasmic dynein to accomplish over forty tasks. To achieve this, the cell uses a complex array of cofactors and regulators to specifically control dynein. But the role of each of these cofactors and regulators in poorly understood. To better understand how dynein is regulated we turn to budding ...
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