Efficacy of red beetroot juice supplementation to improve cardiometabolic health in middle-aged/older adults with overweight or obesity, The
Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in developed societies worldwide. Advancing age is the primary risk factor for CVD, with lifestyle factors such as diet and nutrition also playing a role. Aging results in adverse changes to the arteries including vascular endothelial dysfunction which is characterized by a decline in nitric oxide (NO)-mediated endothelium-dependent dilation, and increased stiffening of large elastic arteries. This age-associated vascular dysfunction is predominantly driven by increased oxidative stress and chronic inflammation and ...
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