Contraception vaccination for mares and its effects on cyclicity and estrous behavior
Overpopulation is an issue for wild horses due to limited forage and decreasing water sources. Sterilizing mares without surgical ovariectomy would be cost effective and safer. There are currently no vaccines that cause permanent sterility in mares. Bone Morphogenetic Protein 15 (BMP-15) and Growth Diﬀerentiation Factor 9 (GDF-9) are oocyte-specific proteins involved in every stage of follicular development from primordial activation through ovulation. This study investigated the effects of a combination vaccine consisting of these oocyte-speciﬁc growth factors, GDF-9 and BMP-15, on mare cyclicity ...
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Embargo Expires: 09/03/2021