Evolution of mutations associated with pyrethroid resistance and the reversal of resistance in Aedes aegypti
Worldwide vector control has been relying heavily on pyrethroid insecticides to reduce Aedes aegypti Linnaeus populations. Pyrethroids are relatively inexpensive, have low vertebrate toxicity, and have been efficient in reducing mosquito populations. Constant use of pyrethroid insecticides, however, has driven mosquito populations to develop resistance over time. In this dissertation, we have tracked the evolution of three mutations in the voltage gated sodium channel (vgsc) that are associated with pyrethroid resistance Aedes aegypti populations in Mexican. These are 410, 1,016 and 1,534, ...
(For more, see "View full record.")