T zone lymphoma: cellular origin and function
The lymphoid system is exceedingly complex with specialized subsets of lymphocytes involved in both the innate and adaptive immune response. Lymphocytes are subdivided into T cells and B cells with lymphoproliferative disorders comprising a heterogeneous group of diseases arising from various lymphocyte subsets. Dogs are a natural model for studying cancer in humans with overlapping subtypes of lymphoproliferative disease seen in both species. We were particularly interested in characterizing lymphoma subtypes in dogs as a model for studying human disease progression. We believe characterization ...
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