Roles of iron, the infrapatellar fat pad, and dietary factors in the Hartley guinea pig model of spontaneous osteoarthritis, The
Osteoarthritis (OA) is the most prevalent musculoskeletal disorder across the world, affecting close to 300 million people. The disease manifests as degeneration and loss of articular cartilage, synovial hyperplasia, formation of osteophytes, subchondral bone remodeling, and joint space narrowing. These changes result in decreased range of motion as well as painful mobility in affected individuals. The knee joint is the most commonly afflicted joint. Osteoarthritic changes may develop secondary to a localized injury, referred to as post-traumatic OA. Degenerative changes can also develop without ...
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