Evaluating luteinizing hormone receptor signaling using the cyclic AMP reporter ICUE3
The luteinizing hormone (LH) receptor is a member of the G protein-coupled receptor family and the subfamily of glycoprotein hormone receptors. The LH receptor plays a vital role in normal development and in the function of the gonads. The LH receptor is expressed in interstitial cells, thecal cells, and granulosa cells and in cells making up the corpus luteum. Signal transduction by LH receptors is dependent on hormone activation of LH receptors and subsequent activation of G proteins. Evaluating the cyclic adenosine monophosphate (cAMP) level in response to binding of ligand to LH receptors ...
(For more, see "View full record.")
Hadhoud, Giuma E.
Roess, Deborah A.; Barisas, George