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    Development of a phage-based diagnostic sensor for active Tuberculosis

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    http://hdl.handle.net/10217/178863
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    Zhao_colostate_0053A_13900.pdf (1.673Mb)
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    Abstract
    Antibodies, the quintessential biological recognition molecules, are not ideal for many applications because of their large size, complex modifications, and thermal and chemical instability. Identifying alternative scaffolds that can be evolved into tight, specific binding molecules with improved physical properties is of increasing interest, particularly for biomedical applications in resource-limited environments. Hyperthermophilic organisms, such as Sulfolobus solfataricus, are an attractive source of highly stable proteins as starting points for alternative molecular recognition scaffolds. ...
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    Author(s)
    Zhao, Ning

    Advisor(s)
    Fisk, John D.

    Date Issued
    2016
    Format
    born digital; doctoral dissertations
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    • 2000-2019 - CSU Theses and Dissertations
    • Theses and Dissertations - Department of Chemical and Biological Engineering

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