Characterization of Brucella infection in ruminant hosts : disease pathogenesis, immunology, and epidemiology
Brucellosis is one of the most common zoonotic diseases worldwide, with endemic disease areas in the Middle East, Mediterranean Basin, Central Asia, Africa, and Central and South America. Disease is caused by various species of the gram negative bacteria Brucella. Infection in humans results primarily from contact with infected livestock or consumption of contaminated livestock products; cattle, small ruminants, and swine are the primary reservoir hosts. Although the Brucella bacterium was discovered over a century ago, control of disease remains a major challenge in many areas worldwide. ...