Seroanalysis of Felis catus gammaherpesvirus 1 infection in domestic cats
We recently described a novel herpesvirus of domestic cats, Felis catus gammaherpesvirus 1 (FcaGHV1). FcaGHV1 is a member of the gammaherpesvirus subfamily, which also includes the human cancer-associated herpesviruses, Epstein-Barr virus (EBV) and Kaposi’s sarcoma-associated herpesvirus (KSHV). To determine FcaGHV1 antigens that elicit a detectable humoral-immune response in naturally-infected domestic cats, I chose to evaluate seven FcaGHV1 proteins. These proteins are conserved across the subfamily and antigenic in other gammaherpesvirus infections. I amplified and cloned each of the seven ...
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