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    Manipulation and characterization of proopiomelanocortin (POMC) neurons in the hypothalamic regulation of energy balance

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    http://hdl.handle.net/10217/167172
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    Abstract
    It is well documented that hypothalamic proopiomelanocortin (POMC) neurons are a critical component in the maintenance of energy balance. POMC neurons release peptide transmitters that modulate pathways involved in food intake, energy expenditure, and reward pathways. POMC peptide release can result in the inhibition of food intake and increased activation of these cells is thought to precipitate the development of anorexia in the activity-based anorexia (ABA) rodent model. Currently, the physiological underpinnings that drive the development of anorexia are not fully understood, but evidence ...
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    Author(s)
    Dennison, Christina Suzanne

    Advisor(s)
    Hentges, Shane T.; Partin, Kathy M.

    Date Issued
    2015
    Format
    born digital; doctoral dissertations
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    • 2000-2019 - CSU Theses and Dissertations
    • Theses and Dissertations - Department of Biomedical Sciences

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