(Colorado State University. Libraries, 2007) Biller, Barbara J., author; Dow, Steve, advisor
Chemotherapy has historically been viewed as immunosuppressive; however studies suggest that some chemotherapeutic agents possess immunostimulatory effects. Despite the promise offered by new treatment modalities such as immunotherapy, novel therapies appear most effective when used in combination with traditional treatments such as chemotherapy. Therefore, there is considerable interest in the identification of chemotherapeutics that can be synergistically combined with cancer immunotherapy. Little is known, however, concerning the immunomodulatory effects of chemotherapy on many aspects of immunity.
