Browsing by Author "Cha, Jongmun, author"
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Item Open Access Occurrence and biodegradation of antibiotic compounds in the aquatic environment(Colorado State University. Libraries, 2007) Cha, Jongmun, author; Carlson, Kenneth H., advisorThe occurrence and fate of antibiotics in the aquatic environment are an emerging area of interest due to the potential impact of these compounds on the environment. This study applied rapid, sensitive and reliable analytical methods for the determination of β-lactam and polyether ionophore antibiotics in surface water, wastewater, sediment, lagoon water, and animal manure. The method incorporated solid-phase extraction and liquid chromatography-ion trap tandem mass spectrometry (LC-MS-MS) with selected reaction monitoring. Specifically, the method was applied to evaluate the occurrence of these compounds in a small watershed in northern Colorado. The study also investigates the potential for on-farm removal of these compounds by measuring the biodegradation kinetics of oxytetracycline, sulfamethoxazole, tylosin, and monensin in bioreactors setup to simulate a dairy wastewater lagoon.