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Browsing by Author "Bosco-Lauth, Angela M., author"

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    Japanese encephalitis virus: pathogenesis and immunity
    (Colorado State University. Libraries, 2010) Bosco-Lauth, Angela M., author; Bowen, Richard, advisor; Quackenbush, Sandra, advisor
    Japanese encephalitis virus (JEV) is a vector-borne disease of Asian origin that has the potential to spread into temperate regions across the globe. The recent incursion of the virus into Northern Australia illustrates its ability to replicate in different vectors and has led to an increase in the need for disease surveillance in the U.S. and other locations. The focus of this dissertation was to investigate the potential of some common North American mosquitoes to transmit JEV and to study the pathogenesis and immunity in animal models, namely horses and hamsters.