Effects of Molecular Genetics on Cancer Management
With the development of next generation sequencing, the availability and effectiveness of genetic cancer panels is at an all-time high. In the past, largely only single gene tests were available to test for the presence of some high penetrance genes, such as BRCA1 and 2. Single gene tests are less likely to give conclusive and clinically useful results due to the limited amount of data collected and heterogeneity of cancers. The benefits of full cancer panels from popular companies such as Myriad, GeneDx, and Ambry Genetics include greater sensitivity results and therefore a more conclusive ...
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