Functions and Mutations of the Proapoptotic Protein bax in Yeast Cells
Recent research has shown there is a direct connection between the mitochondrial outer membrane and the endoplasmic reticulum. In light of this information, the purpose of this research project was to determine whether the proapoptotic protein bax uses this connection as a mechanism of entry into the outer membrane of mitochondria. The major goal of this research effort is determine if changes in the interaction of the mitochondria and the endoplasmic reticulum (ER) interaction will affect, either positively or negatively, the activities of the bax protein. To determine this, a group of mutations ...
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