Release of bioactive agents from mesoporous silica nanoparticles for biological applications
The high surface area, pore volume, and biocompatible/ biodegradable silica matrix of mesoporous silica nanoparticles (MSN) has led to extensive investigation into these materials as carriers for bioactive agents. These agents can be loaded into and sheltered within the mesopores, then released at the target site either through simple diffusion or in response to specific stimuli. Owing to the facile surface modification of MSN, stimuli responsive MSN is frequently synthesized through the covalent linkage of an organic functionality, capable of changing conformation in response to a given stimuli, ...
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