Now showing items 31-40 of 4377
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Involvement of mitochondrial protein post translational modification in the pathogenesis of alcoholic liver disease
Chronic alcohol consumption is a major cause of several diseases including alcoholic liver disease (ALD). Several mechanisms contribute to the initiation and the progression of ALD including mitochondrial dysfunction. ...
Effect of traumatic brain injury State laws on incident and recurrent concussion rates, The
Author(s):Arakkal, Alan Tom
Importance: Comprehensive nationwide evaluation of state traumatic brain injury (TBI) laws is vital given growing populations of high school athletes. Objective: To evaluate the effectiveness of state level TBI legislation ...
Dietary patterns and metabolomics in the nutrition etiology of type 1 diabetes
Author(s):Johnson, Randi K.
The incidence of type 1 diabetes (T1D) is increasing worldwide, likely due to the increase (or decrease, if protective) of key non-genetic factors. Though diet has been implicated in T1D development, its role is poorly ...
Precision therapeutic approach to autoimmunity caused by PI3K pathway dysregulation, A
Author(s):Franks, Sarah Elizabeth
GWAS and candidate studies have identified risk-conferring allelic variants that impair the ability to maintain immune tolerance. Several of these risk alleles are thought to function in B cell signaling, including negative ...
Using optogenetics and biochemistry to uncover how autophagy regulates cell death
Author(s):Fitzwalter, Brent Eugene
Macroautophagy (autophagy) is intimately linked with cell death and often allows cancer cells to evade apoptosis. This has prompted clinical trials to combine autophagy inhibitors with other drugs with the aim of reducing ...
Transpersonal caring relationships as part of an online nursing education environment
Author(s):Gdanetz, Lorraine Marie
An interpretive descriptive qualitative methodological approach underpinned by Caring Science Theory, Relational Caring Inquiry coupled with Aesthetic Ways of Knowing was utilized to discover the meaning of a transpersonal ...
Professional APCs are involved in the recruitment and activation of T cells within the islets during Type 1 diabetes progression
Author(s):Sandor, Adam Miklos
Type 1 diabetes (T1D) is caused by the T cell mediated autoimmune destruction of the insulin-producing β cells within the pancreatic islets. Along with T cells, professional antigen presenting cells (APCs) are also required ...
Agility poet study : agility, patient outcomes, and environmental turbulence in acute care nursing practice settings, The
Author(s):Snyder, Kara Adams
The nursing environment has been cited as a pivotal organizational factor in safety and quality and yet the practice environment is described as turbulent, in a state of unrest, disturbance, agitation or commotion. ...
Applications of policy analysis on health outcomes
Author(s):Richardson, Zachary Samuel
Policy analysis as a tool for determining the effects of health outcomes is an increasingly common practice but has been limited in scope to considering largely federal or state law changes only. My dissertation demonstrates ...
Comparison of one year post-injury outcomes between intensive locomotor training and conventional therapy after motor incomplete spinal cord injury
Author(s):Tefertiller, Candace Rae
Background: Spinal cord injury (SCI) is often a devastating condition that negatively affects an individual’s physical, psychological, and social well-being requiring extensive rehabilitation. The majority of all SCIs are ...