Risk factors for kaposi sarcoma-associated herpesvirus (KSHV) and kaposi sarcoma (KS) mortality in sub-Saharan Africa, The
The largest worldwide burden of Kaposi sarcoma (KS), 85% of all cases, is found in sub-Saharan Africa. Kaposi sarcoma-associated herpesvirus (KSHV) is the etiological agent for KS. KSHV seroprevalence is inconsistent across and within countries which suggests environmental factors contribute to KSHV susceptibility and infection. Sub-Saharan Africa has up to 95% seropositive rates in some populations and is also malaria endemic, principally caused by Plasmodium falciparum (Pf). The geographic concordance of these two infections, together with malaria’s ability to depress the immune system led to ...
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Sabourin, Katherine R.