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Allostery in the dengue virus NS3 helicase: Insights into the NTPase cycle from molecular simulations.
Contributor:McCullagh, Martin; Davidson, Russell; Hendrix, Josie; Geiss, Brian
Date:2018-03-01
Date:2018-03-01
The C-terminus domain of non-structural 3 (NS3) protein of the Flaviviridae viruses (e.g. HCV, dengue, West Nile, Zika) is a nucleotide triphosphatase (NTPase) -dependent superfamily 2 (SF2) helicase that unwinds double-stranded ...