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Western equine encephalitis virus : neuroinvasion, pathogenesis, and immunomodulatory treatment strategies
Contributor:Phillips, Aaron Timothy
Western equine encephalitis virus (WEEV; Alphavirus) is a mosquito-borne virus that can cause severe encephalitis in humans and equids. WEEV is closely-related to eastern equine encephalitis virus (EEEV) and may model ...
Characterizing the role of the HspX protein from Mycobacterium tuberculosis as a subunit vaccine candidate in the small animal model of tuberculosis
Contributor:Wieczorek, Agatha E.
Tuberculosis (TB) is a bacterial disease of the lung, caused by Mycobacterium tuberculosis, and currently remains an important human pathogen. The only vaccine against tuberculosis licensed for human use is a live, attenuated ...
Mining the Francisella tularensis proteome for vaccine candidates
Contributor:White, Kimberly G.
Based on methodologies developed for the identification of T cell antigen of other intracellular bacterial pathogens, a proteomic approach was applied for the elucidation of T cell antigens of Francisella tularensis (Covert, ...
HIV prophylaxis : an essential role for T cells and adjuvants in recombinant mucosal Lactobacillus acidophilus vaccines
Contributor:LeCureux, Jonathan Spicer
Current HIV vaccines have poor efficacy, with inconsistent levels of protection following mucosal HIV exposure. Lactic acid bacteria offer an alternative vaccine vector targeting the primary site of HIV infection, the ...
The analysis of Burkholderia pseudomallei virulence and efficacy of potential therapeutics
Contributor:Propst, Katie L.
Burkholderia pseudomallei is the causative agent of the disease melioidosis and is classified as a category B Select Agent. There are currently many challenges associated with both the study of this pathogen and its treatment ...
Cationic liposome-DNA complex-based immunotherapeutic and immunization strategies for control of la Crosse virus and Leishmania major infections
Contributor:Arthun, Erik Norden
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