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Chronic wasting disease: a model for prion transmission via saliva and urine
Author(s):Haley, Nicholas James
Date Issued:2010
Format:born digital; doctoral dissertations
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Oral and nasal mucosal pathways of prion infection in chronic wasting disease
Author(s):Denkers, Nathaniel David
Date Issued:2010
Format:born digital; doctoral dissertations
Chronic wasting disease (CWD) is a fatal neurodegenerative prion disease of deer, elk, and moose. The unique feature of CWD as a prion disease is its efficient transmission among cervids in nature. As with other prion ...
Elucidating mother to offspring transmission of chronic wasting disease using a transgenic mouse model
Author(s):Willingham, Kassandra
Date Issued:2016
Format:born digital; masters theses
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE), or prion disease, of free-ranging and farmed cervids (deer, elk and moose). CWD is the only TSE in a wildlife population, which was initially ...
Chronic wasting disease in transgenic mice and white-tailed deer - prion trafficking and pathogenesis
Author(s):Seelig, Davis Martin
Date Issued:2010
Format:born digital; doctoral dissertations
Chronic wasting disease (CWD) is a naturally occurring, horizontally transmitted prion disease of cervids, including deer, elk and moose. Typical of all prion diseases, CWD is characterized by the forced conversion of the ...
Role of plants as an environmental reservoir of chronic wasting disease prions, The
Author(s):Ortega, Aimee Elise
Date Issued:2016
Format:born digital; masters theses
Transmissible Spongiform Encephalopathies (TSEs) are a group of diseases caused by an abnormal version, PrPRES, of the normal cellular host protein prion protein (Prnp) termed PrPC. Disease is fatal resulting in amyloid ...
Longitudinal characterization of peripheral prion pathogenesis in Syrian hamsters experimentally inoculated with hamster-adapted Transmissible Mink Encephalopathy
Author(s):Lee, Erin
Date Issued:2017
Format:born digital; masters theses
Transmissible Spongiform Encephalopathies (TSEs) are a group of infectious, neurodegenerative diseases affecting animals, including humans. Caused by misfolded proteins called prions, TSEs are characterized by a long, ...
Prion strain adaptation: breaking and building species barriers
Author(s):Reid, Crystal Meyerett
Date Issued:2014
Format:born digital; doctoral dissertations
Prions have been an enigma to researchers and agricultural producers alike since their inception. The timing and order of prion disease discovery can be attributed to the scrutiny of the prion protein-only hypothesis. The ...
Occurrence of CWD prions and their risk to humans, The
Author(s):Davenport, Kristen Anne
Date Issued:2017
Format:born digital; doctoral dissertations
Zoonotic diseases are often caused by viruses or bacteria, which adapt to new species with changes to their nucleic acid sequence. The etiologic agent of transmissible spongiform encephalopathies (TSEs), the prion, is a ...
Chronic wasting disease strain diversity, distribution and transmission
Author(s):Wagner, Kaitlyn
Date Issued:2021
Format:born digital; doctoral dissertations
Chronic wasting disease (CWD) is an invariably fatal prion disease affecting captive and free-ranging cervids, including white-tailed deer, mule deer, moose, elk and reindeer. Since the initial discovery of the disease in ...