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Longitudinal characterization of peripheral prion pathogenesis in Syrian hamsters experimentally inoculated with hamster-adapted Transmissible Mink Encephalopathy
Author(s):Lee, Erin
Date Submitted:2017
Transmissible Spongiform Encephalopathies (TSEs) are a group of infectious, neurodegenerative diseases affecting animals, including humans. Caused by misfolded proteins called prions, TSEs are characterized by a long, ...
Role of plants as an environmental reservoir of chronic wasting disease prions, The
Author(s):Ortega, Aimee Elise
Date Submitted:2016
Transmissible Spongiform Encephalopathies (TSEs) are a group of diseases caused by an abnormal version, PrPRES, of the normal cellular host protein prion protein (Prnp) termed PrPC. Disease is fatal resulting in amyloid ...
Elucidating mother to offspring transmission of chronic wasting disease using a transgenic mouse model
Author(s):Willingham, Kassandra
Date Submitted:2016
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE), or prion disease, of free-ranging and farmed cervids (deer, elk and moose). CWD is the only TSE in a wildlife population, which was initially ...
Prion strain adaptation: breaking and building species barriers
Author(s):Reid, Crystal Meyerett
Date Submitted:2014
Prions have been an enigma to researchers and agricultural producers alike since their inception. The timing and order of prion disease discovery can be attributed to the scrutiny of the prion protein-only hypothesis. The ...
Occurrence of CWD prions and their risk to humans, The
Author(s):Davenport, Kristen Anne
Date Submitted:2017
Zoonotic diseases are often caused by viruses or bacteria, which adapt to new species with changes to their nucleic acid sequence. The etiologic agent of transmissible spongiform encephalopathies (TSEs), the prion, is a ...
Chronic wasting disease: a model for prion transmission via saliva and urine
Author(s):Haley, Nicholas James
Date Submitted:2010
To view the abstract, please see the full text of the document.
Oral and nasal mucosal pathways of prion infection in chronic wasting disease
Author(s):Denkers, Nathaniel David
Date Submitted:2010
Chronic wasting disease (CWD) is a fatal neurodegenerative prion disease of deer, elk, and moose. The unique feature of CWD as a prion disease is its efficient transmission among cervids in nature. As with other prion ...
Chronic wasting disease in transgenic mice and white-tailed deer - prion trafficking and pathogenesis
Author(s):Seelig, Davis Martin
Date Submitted:2010
Chronic wasting disease (CWD) is a naturally occurring, horizontally transmitted prion disease of cervids, including deer, elk and moose. Typical of all prion diseases, CWD is characterized by the forced conversion of the ...