Michael, James A., II, authorPopat, Ketul C., advisorLi, Vivan, committee memberSampath, Walajabad S., committee member2023-01-212023-01-212022https://hdl.handle.net/10217/235977316L stainless steel (SS) is widely used biomaterial for implantable devices and is estimated to the base material for 60% of implantable devices. However, one challenge of the material is the inhomogeneity of the surface morphology which may influence the adhesion process of host cells and bacteria. One method to create a uniform surface of 316L SS is plasma electrolytic oxidation (PEO). PEO creates an oxide layer on the outer surface thus changing the surface topography on the microscale. PEO process on SS functions by anodizing the surface via direct current in electrolyte solution. Preliminary research found that a continuous direct current over a time manufactured undesirable samples, to overcome this challenge the use of pulse timings was utilized during fabrication. This research aimed to answer the questions how do PEO modifications effect cellular adhesion and viability, and how do PEO modifications affect bacteria adhesion and viability. PEO modified 316L SS surfaces were characterized and its effects on the adhesion, morphology, and differentiation of adipocyte derived stem cells, along with the adhesion and morphology of Staphylococcus aureus was investigated.born digitalmasters thesesengCopyright and other restrictions may apply. User is responsible for compliance with all applicable laws. For information about copyright law, please see https://libguides.colostate.edu/copyright.Text